PRODUCT >> Fine Chemicals

Product Name

CAS No.

N-(3-sulfopropyl)- 3-Methoxy-5-Methylaniline

766502-50-5


Product Name (品名):

N-(3-sulfopropyl)- 3-Methoxy-5-Methylaniline

N-(3-磺酸丙基)-3-甲氧基-5-甲基苯胺

Appearance(外观):grey powder solid

Molecular Formula (分子式):

C11H17NO4S

Molecular Weight (分子量):

259.32

Purity (纯度):

98%

Production Capacity (产能)500KG/ Year

Specification:(指标)

MS, HNMR, Purity 98%

Contact Telephone (联系电话):

023-677770219

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Sales Department

Contact Email:

sales@chemieliva.com

用途

  • 生化与临床诊断检测

    • 过氧化氢相关指标检测:作为显色底物,在过氧化物酶(POD/HRP)存在下,与 4 - 氨基安替比林(4-AA)或 3 - 甲基苯并噻唑砜腙(MBTH)发生氧化偶合反应,生成稳定的有色染料,通过比色法测定体系中过氧化氢的含量,进而间接检测与过氧化氢生成相关的生化指标,如血糖、尿酸、胆固醇、甘油三酯等。例如在血糖检测中,葡萄糖氧化酶催化葡萄糖生成葡萄糖酸和过氧化氢,该化合物与 4-AA 在过氧化物酶作用下显色,吸光度变化与血糖浓度成正比,可用于血糖代谢项目中葡萄糖检测试剂和糖化白蛋白检测试剂的制备。

    • 酶活性测定:用于测定产生过氧化氢的酶类活性,如葡萄糖氧化酶、尿酸酶、胆固醇氧化酶等,在酶动力学研究和酶活性的定量分析中发挥作用,为相关疾病的诊断和病情监测提供依据。例如,在腺苷脱氨酶(ADA)活性检测中,由该化合物等组成的检测试剂具有显色效果好、反应迅速、稳定性和精密度高的优势,能作为反映肝脏损伤的敏感指标,用于肝功能的常规检查。

  • 科研与试剂开发

    • 生化实验研究:在生物化学研究中,用于建立各类基于 Trinder 反应的检测方法,研究代谢途径中相关物质的变化,为生命科学研究提供工具。

    • 诊断试剂研发:作为关键原料用于研发临床生化诊断试剂盒,其高水溶性、显色反应产物紫外吸收大于 540nm、对 pH 范围要求较宽、反应灵敏度较高等优点,能保证多种酶的活性,可用于极微量待测物的测定,适用于自动化生化分析系统。

  • 其他潜在用途

    • 染料合成中间体:其分子结构中的磺酸基和氨基具有反应活性,可用于合成特定的染料或颜料,尤其在开发水溶性染料方面具有潜力,适用于纺织、造纸和印刷等行业。

    • 有机合成中间体:可用于合成其他功能性化合物,如医药、农药等领域的中间体,拓展其在精细化工领域的应用。

Function

  1. 1. Biochemical and clinical diagnostic detection

  2. Detection of hydrogen peroxide-related indicators: As a chromogenic substrate, it undergoes an oxidative coupling reaction with 4-aminoantipyrine (4-AA) or 3-methylbenzothiazolones hydrazone (MBTH) in the presence of peroxidase (POD/HRP) to form a stable colored dye. The content of hydrogen peroxide in the system is determined by colorimetry, and then the biochemical indicators associated with hydrogen peroxide generation (e.g., blood glucose, uric acid, cholesterol, triglycerides) are indirectly detected. For example, in blood glucose detection, glucose oxidase catalyzes the conversion of glucose to gluconic acid and hydrogen peroxide; this compound then reacts with 4-AA for color development under the action of peroxidase. The absorbance change is proportional to the blood glucose concentration, making it applicable for the preparation of detection reagents for glucose in blood glucose metabolism assays and glycated albumin detection reagents.

  3. Enzyme activity measurement: It is used to determine the activity of hydrogen peroxide-generating enzymes (e.g., glucose oxidase, uricase, cholesterol oxidase), playing a role in enzyme kinetic research and quantitative analysis of enzyme activity, and providing a basis for the diagnosis and condition monitoring of related diseases. For instance, the detection reagent composed of this compound and other components exhibits the advantages of good color development effect, rapid reaction, high stability and precision in the activity detection of adenosine deaminase (ADA). It can serve as a sensitive indicator reflecting liver injury and is used for routine liver function tests.

  4. 2. Scientific research and reagent development

  5. Biochemical experimental research: In biochemical research, it is used to establish various detection methods based on the Trinder reaction, study the changes of related substances in metabolic pathways, and provide tools for life science research.

  6. Diagnostic reagent R&D: As a key raw material, it is used in the research and development of clinical biochemical diagnostic kits. Its advantages such as high water solubility, the ultraviolet absorption of chromogenic reaction products being over 540 nm, a wide pH range requirement, and high reaction sensitivity can ensure the activity of various enzymes. It is suitable for the determination of trace analytes and automated biochemical analysis systems.

  7. 3. Other potential applications

  8. Intermediate for dye synthesis: The sulfonic acid group and amino group in its molecular structure have reaction activity, enabling it to be used in the synthesis of specific dyes or pigments. It has great potential especially in the development of water-soluble dyes, and is applicable to the textile, papermaking, printing and other industries.

  9. Intermediate for organic synthesis: It can be used to synthesize other functional compounds, such as intermediates in the pharmaceutical and pesticide fields, expanding its applications in the fine chemical industry.

Structure (结构式):

 

N-(3-sulfopropyl)- 3-Methoxy-5-Methylaniline

N-(3-磺酸丙基)-3-甲氧基-5-甲基苯胺


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Standard InChI: 

InChI=1S/C11H17NO4S/c1-9-6-10(8-11(7-9)16-2)12-4-3-5-17(13,14)15/h6-8,12H,3-5H2,1-2H3,(H,13,14,15)


Standard InChIKey: 

DYPGTLUYQZIULN-UHFFFAOYSA-N


SMILES: 

S(=O)(=O)(O)CCCNC1=CC(=CC(=C1)C)OC

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Product link:  https://www.chemieliva.com/product_content-25-15673666.html?CASNo=2533349-57-2 

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Supplying Capacity: 3000KG/Year

Structure:


Product Name:4-(Bicyclo[2.2.1]Heptan-2-yl)-N-(4-Cyclohexylphenyl)Aniline

中文名:4-二环[2.2.1]庚-2-基-N-(4-环己基苯基)-苯胺

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